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This structural modification significantly reduces its affinity for IGF binding proteins (IGFBPs), increases the free concentration, and enhances its biological activity by more than three times compared to natural IGF-1

Muthuraman A, Singh N

Les essais cliniques montrent un signal : la supplmentation orale 250-500 mg/jour pendant 4 12 semaines rduit modestement l'indice de mlanine, principalement dans les zones cutanes exposes au soleil